Autoimmune cholangitis within the spectrum of autoimmune liver disease
نویسندگان
چکیده
منابع مشابه
A spectrum of histopathologic findings in autoimmune liver disease.
We retrospectively studied 42 liver biopsy specimens from 39 patients who met serologic and histologic criteria of autoimmune liver diseases. We found 10 cases of overlap syndrome (OLS), 10 autoimmune cholangitis (AIC), 10 primary biliary cirrhosis (PBC), and 9 autoimmune hepatitis (AIH) type 1. The following results were obtained: (1) Granulomas and biliary duct lesions were more prominent in ...
متن کاملAutoimmune liver disease.
• The diagnosis of autoimmune hepatitis is based on specific immunological, histological and biochemical characteristics after exclusion of other causes of liver disease including viral hepatitis. • Hepatitis E virus infection should be considered in the differential diagnosis of autoimmune hepatitis. • Prednisone, prednisolone, or budesonide are first line treatment options for autoimmune hepa...
متن کاملAutoimmune liver disease
Autoimmunity is regarded as the main mechanism involved in pathogenesis of various liver diseases, such as autoimmune hepatitis (ÁIÇ), primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), autoimmune cholangitis, overlap syndromes AIH-PBC and AIH-PSC and liver dysfunction due to connective tissue diseases. Autoimmune hepatitis is an immune-mediated, autodestructive liver diseas...
متن کاملAutoimmune Cholangitis: A Variant Syndrome of Autoimmune Hepatitis
Autoimmune cholangitis (AIC) or autoimmune cholangiopathy is a chronic inflammation of liver and a variant syndrome of autoimmune hepatitis (AIH). We present a case of an adult female who had biochemical features of cholestasis and transaminasemia but aminotransferases were not in the hepatitis range and had histological evidence of bile duct injury which was subsequently diagnosed as autoimmun...
متن کاملOverlap syndrome: autoimmune sclerosing cholangitis.
A 9-year-old-girl presented with clinical features of autoimmune hepatitis and associated signs of cholestasis in the form of itching and elevated levels of serum alkaline phosphatase. There was histologic evidence of bile duct injury. Hence a clinical diagnosis of "overlap syndrome" of autoimmune hepatitis with primary sclerosing cholangitis was considered.
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ژورنال
عنوان ژورنال: Hepatology
سال: 2000
ISSN: 0270-9139
DOI: 10.1053/jhep.2000.7878